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| Effect of modified B-lynch suture combined with mifeprestone for treating women with cesarean section because of central placenta previa complicated with placenta implantation, and its influence on the coagulation indicator of the women |
| Wuhu Hospital of Traditional Chinese Medicine, Anhui Province, 241000 |
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Abstract To investigate the clinical effect of modified B-lynch suture combined with mifeprestone for treating women with cesarean section because of central placenta previa and placenta implantation, and to study its influence on the values of platelet, prothrombin time (PT), and activated partialthromboplastin time (APTT). Methods: The clinical data of 60 women with central placenta previa complicated with placenta implantation from June 2015to December 2020 were collected and analyzed retrospectively. According to the treatment methods, these women were divided into group A (26 women given conventional treatment) and group B (34 women given modified B-lynch suture combined with mifeprestone). The clinical effective rate, the intraoperative and postpartum blood loss, and the levels of postpartum hemoglobin and coagulation factors of the women were compared between the two groups. Results: The clinical effective rate (94.1%) of the women in group B was significant higher than that (84.6%) of the women in group A, and the amount of intraoperative blood loss (521.3±24.4ml), 2h postpartum blood loss (328.24± 52.2ml), and 24h postpartum blood loss (398.6±41.7ml) of the women in group B were significant lower than those of the women in group A. The hemoglobin level (142.15±2.41 g/L) in 24h postpartum of the women in group B was significant higher than that of the women in group A. The values of platelet (258.30±40.02×109/L), APTT (27.45±3.23s) and PT (11.21±0.35s) of the women in group B were significant lower than those of the women in group A, abut he level of Fibrinogen (2.85±0.55 g/L) of the women in group B was significant higher (all P＜0.05). Conclusion: The modified B-lynch suture combined with mifeprestone for treating the women with cesarean section because of central placenta previa complicated with placenta implantation can effectively reduce the hemorrhage and can improve the levels of coagulation factors of the women with better clinical efficacy.
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