|
|
|
| Relationship between the expression levels of angiogenin-1, CD1a, and CD56 of the women with medical abortion by mifepristone and their abnormal uterine bleeding |
| 1. Fuyang Traditional Chinese Medicine Hospital, Fuyang, Anhui Province, 236025；2. Fuyang People's Hospital |
|
|
|
|
Abstract To analyze the change of the expression levels of plasma angiogenin-1 (Ang-1), and the CD1a, and CD56 in fetal sac tissue of the women with abnormal uterine bleeding after medical abortion by mifepristone. Methods: 85 women after medical abortion by mifepristone were included and were divided into group A (women with abnormal uterine bleeding >14d) and group B (women with uterine bleeding <14d). Radioimmunoassay was used to detect the plasma Ang-1 level, and immunohistochemical method was used to detect the CD1a and CD56 levels in fetal sac tissue. Logistics regression model was used to analyze the relationship between the expression levels of Ang-1, CD1a, and CD56 of the women with medical abortion by mifepristone and their abnormal uterine bleeding. Results: The levels of Ang-1 (365.38±32.15 ng/L), CD1A (25.38±5.21%), and CD56 (15.81±3.39%) of the women in group A were significant higher than those (258.67±28.91 ng/L, 8.65%±2.13%, and 5.68%±1.58%) of the women in group B (P＜0.05). The high levels of Ang-1, CD1A, and CD56 expression were the independent risk factors of abnormal uterine bleeding of the women after medical abortion by mifepristone (P＜0.05). Conclusion: The levels of Ang-1, CD1a and CD56 the women with abnormal uterine bleeding after medical abortion by mifepristone are abnormally high expression, and the high levels of Ang-1, CD1A, and CD56 expression are all the independent risk factors of their abnormal uterine bleeding occurrence.
|
|
|
|
|
|
|
|
|
