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| Analysis of the levels of plasma homocysteine, cystatin C，and high sensitivity C-reactive protein in prognosis evaluation of pregnant women with gestational hypertension |
| Mianyang Central Hospital, Sichuan Province, 621000 |
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Abstract To study the levels of plasma homocysteine (Hcy), cystatin C (Cys C)，and high sensitivity C-reactive protein (hs CRP) in prognosis evaluation of pregnant women with gestational hypertension. Methods: The clinical data of 126 pregnant women with gestational hypertension from January 2019 to December 2019 were collected and included in observation group, and 126 normal pregnant women were selected in control group during the same period. The plasma Hcy, Cys C，and hs CRP) levels of the women in the two groups were detected and compared. The pregnancy outcomes of the women in the two groups were statistics analyzed. Results: The levels of plasma Hcy (18.7±3.9 umol/L), Cys C (1.5±0.5 mg/L), and hs-CRP (5.7±1.6 mg/L) of the women in the observation group were significant higher than those (5.1±1.4 umol/L, 0.8±0.1 mg/L, and 2.5±0.5Mg /L) of the women in control group (P＜0.05). The incidence of adverse pregnancy outcome (65.9%) of the women in the observation group was significant higher than that (18.3%) of the women in the control group (P＜0.05). Plasma levels of Hcy, Cys C, and hs-CRP were positively correlated with the occurrence of gestational hypertension (r=0.589, 0.678, 0.782, all P＜0.05). Conclusion: The detection of plasma Hcy, Cys C and hs-CRP levels has some clinical significance in the prognosis evaluation of pregnant women with gestational hypertension.
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