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| Effects of vaginal hysteromyomectomy on perioperative indexes and complications occurrence |
| Guang'an People's Hospital, Guang'an, Sichuan Province, 638000 |
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Abstract To explore the effects of vaginal hysteromyomectomy of patients with uterine fibroids on their perioperative indexes and complications occurrence. Methods: 78 patients with uterine fibroids were randomly divided into group A (patients experinced laparotomy hysteromyomectomy) and group B (patients experinced vaginal hysteromyomectomy). The perioperative indexes, postoperative condition, and the rate of complications of the patients in the two groups were observed. The sex hormones levels, ovarian function, sexual function, and serum biochemical indicators levels of the patients in the two groups were compared between before operation and in the 6th month after operation. Results: The operative time, the postoperative exhaust time, and the postoperative hospitalization time of the patients in group B were significant shorter than those of the patients in group A, the amount of postoperative blood loss of the patients in group B was significant less than that of the patients in group A, and the rate of postoperative analgesics application of the patients in group B was significant lower than that of the patients in group A. The total incidence of complications (5.1%) of the patients in group B was significant lower than that (20.5%) of the patients in group A (all P＜0.05). One week after operation, the levels of serum interferon-γ (IFN-γ), angiotensin II (Ang II), ischemic-modified albumin (IMA), and average myoglobin (MYO) of the patients in group A had increased significantly (P＜0.05), while which of the patients in group B had no changed significantly (P＞0.05), and which of the patients in group A had no significant different from those of the patients in group B (P＜0.05). Six months after operation, the serum estradiol level of the patients in both groups had decreased significantly, while the levels of follicle-stimulating hormone and luteinizing hormone had increased significantly, and the serum estradiol level of the patients in group B was significant higher than that of the patients in group A (all P＜0.05). Six months after operation, the ovarian function score of the patients in both groups had increased significantly, and the score by International Female Sexual Function Assessment Scale (BISF-W) of the patients in both groups had decreased significantly, and the change range of BISF-W score of the patients in group B was significant less than that of the patients in group A (all P＜0.05). Conclusion: Vaginal hysteromyomectomy for treating patients with uterine fibroids can effectively shorten the operative time, promote the postoperative rehabilitation, and effectively improve the postoperative oxidative stress injury, which’s effect is superior to that of traditional laparotomy hysteromyomectomy.
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