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| Effect of laparoscopic hysteromyomectomy for treating women with uterine fibroids on their uterine microcirculation and the subsequent pregnancy |
| Gong'an County Hospital of Traditional Chinese Medicine, Jingzhou , Hubei Province，434000 |
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Abstract To explore the effect of laparoscopic hysteromyomectomy for treating women with uterine fibroids on their uterine microcirculation and the pregnancy later. Methods: 180 women with uterine fibroids were selected and divided into observation group (n=91) and control group (n=89) according to the operation method from January 2017 to January 2020. The women in the control group were treated with laparotomy hysteromyomectomy, and the women in the observation group were treated with laparoscopic hysteromyomectomy. The surgical situation, blood perfusion, capillary diameter, the values of vascularization index (VI), blood flow index (FI), vascularized blood flow index (VFI), the situation of pregnancy later, the serum progesterone (P) and estradiol (E2) levels, and the incidence of adverse reactions of the women were compared between the two groups. Results: The operation time (105.5±19.1min) of the women in the observation group was significant higher than that of the women in the control group, but the blood loss (61.3±12.4ml), anal exhaust time (12.1±3.3h), the time of off-bed for activity (1.3±0.8d), and hospital stay (3.1±1.2d) of the women in the observation group were significant lower (P＜0.05). After treatment, the blood perfusion, the capillary diameter, and the values of VI, FI, and VFI of the women in both groups had increased significantly, which of the women in the observation group were significant higher than those of the women in the control group (P＜0.05). There was no significant difference in the incidence of miscarriage of the women between the two groups. The time from operation to pregnancy later (11.6±4.3 months) and the rate of premature birth (5.5%) of the women in the observation group were lower than those of the women in the control group, but the rate of full-term birth (76.9%) was significant higher (P＜0.05). After treatment, the levels of P and E2 of the women in both groups had decreased significantly, which of the women in the observation group was significant lower than those of the women in the control group (P＜0.05). The incidence of complications (8.8%) of the women in the observation group was significant lower than that (27.0%) of the women in the control group (P＜0.05). Conclusion: Laparoscopic hysteromyomectomy for treating women with uterine fibroids has significant effect, which can effectively improve the uterine microcirculation and pregnancy later, with less complications.
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