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| Effect of levonorgestrel intrauterine contraceptive system combined with laparoscopy for treating patients with stage Ⅲ/Ⅳ endometriosis |
| The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, 450000 |
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Abstract To explore the therapeutic effect of levonorgestrel intrauterine system combined with laparoscopic conservative surgery in patients with stage III/IV endometriosis, and to provide reference for clinical treatment decisions. Methods: 90 patients with stage III/IV endometriosis who underwent laparoscopic conservative surgery were selected as observation objects from July 2018 to December 2019, and they were divided into two groups (45 cases in each group) according to the demand of baby. The women in the observation group were given levonorgestrel intrauterine contraceptive system, and the women in the control group were treated with leuprolide acetate subcutaneous injection. The dysmenorrhea degree and pelvic pain situation of the women in the two groups were evaluated by visual analogue score. The rates of endometriosis recurrence and adverse reaction of the women in the two groups were statistics analyzed. Results: After treatment, there were no significant differences in dysmenorrhea degree (7.2±4.0 points vs. 8.1±4.1 points) and menstrual volume (108.2±13.4ml vs. 106.8±14.0ml) of the women between the two groups (P＞0.05). The score of pelvic pain (6.1±1.1 points) during menstrual interval of the women in the observation group was significant lower than that (6.6±1.3 points) of the women in the control group (P＜0.05). The endometriosis recurrence rate of the women in the observation group (6.7%) had no significant different from that (20.0%) of the women in the control group (P＞0.05). The incidence of adverse reaction (28.9%) of the women in the observation group was significant lower than that (48.9%) of the women in the control group (P＜0.05). Conclusion: Levonorgestrel intrauterine contraceptive system combined with laparoscopic conservative surgery for treating women with stage III/IV endometriosis can effectively reduce the incidences of their menstrual interval pelvic pain and adverse reaction.
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