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| Efficacy of mifepristone combined with different drugs for treatment of uterine cavity residues after medical induced abortion |
| Northwest Women and Children's Hospital, Xi 'an, Shaanxi Province, 710061 |
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Abstract To investigate the clinical effect of mifepristone combined with different drugs for treating uterine cavity residues after medical induced abortion. Methods: A retrospective study was used to select 312 women who had been diagnosed as uterine cavity residues after induced abortion and had been treated by drugs conservatively from January 1, 2016 to December 31, 2017. According to the treatment methods, these women were divided into three groups, and the therapeutic effects of the women in the three groups were compared. Results: The success rate of the therapy by mifepristone combined with oxytocin spray or oxytocin intramuscular injection was significant higher than that by mifepristone combined with motherwort capsule (P<0.05). The bleeding time and amount after the therapy by mifepristone combined with oxytocin spray or oxytocin intramuscular injection were significant less than thoase by mifepristone combined with motherwort capsule treatment (P<0.05). There were no significant differences in negative conversion rate and negative conversion time of hCG among the three groups (P>0.05). The compliance and satisfaction of the therapy by mifepristone combined with oxytocin spray or motherwort capsule was significant higher than that by mifepristone combined with oxytocin intramuscular injection (P<0.05). No serious adverse reactions occurred in the three groups during treatment, and there was no significant difference in adverse reaction rate among the three groups (P>0.05). Conclusion: Mifepristone combined with oxytocin intramuscular injection or oxytocin nasal spray can effectively promote the discharge of uterine cavity residues, and the treatment compliance and satisfaction of the women by mifepristone combined with oxytocin nasal spray are higher.
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