To investigate the curative effect of combination of traditional Chinese and western medicine for treating the pregnant women with liver stagnation and spleenkidney deficiency type threatened abortion and subchorionic hematoma (SCH) during the first trimester of pregnancy. Methods: 200 pregnant women with combination of traditional Chinese and western medicine for treating their liver stagnation and spleen-kidney deficiency type threatened abortion and SCH during the first trimester of pregnancy were selected as the research objects from October 2016 to March 2019. These women were divided into observation group and control group (100 cases in each group) by random number table method. The women in the control group were treated with dydrogesterone, the women in the observation group were treated with dydrogesterone combined with Bushen jianpi huoxue method. The curative effect of the women was compared between the two groups. Results: The effective rate (98.0%) of the women in the observation group was significant higher than that (89.0%) of the women in the control group (P＜0.05). After treatment, the TCM symptom scores of vaginal bleeding, lower abdominal swelling, waist acid, abdominal pain, dizziness and tinnitus of the women in the two groups had decreased significantly, and which of the women in the observation group were significant lower than that of the women in the control group. The pregnancy outcomes, such as the rates of full-term delivery (88.0%) and abortion (6.0%) of the women in the observation group were significant better than those (75.0% and 15.0%) of the women in the control group (P＜0.05), and the incidences of postpartum hemorrhage (5.3%) and placental adhesion (2.1%) of the women in the observation group were significant lower than those (15.3% and 10.6%) of the women in the control group (P＜0.05). Conclusion: The combination of traditional Chinese and western medicine for treating the pregnant women with liver stagnation and spleen-kidney deficiency type threatened abortion and SCH during the first trimester of pregnancy has definite curative effect, which can improve the clinical symptoms and pregnancy outcomes significantly.