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| Effect of high-intensity ultrasound focusing treatment of uterine myoma |
| Baoji People's Hospital, Baoji, Shaanxi Province, 721000 |
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Abstract To study the effect of high-intensity ultrasound focused ultrasound (HIFU) for treating women with uterine myoma, and to analyze its influence on their levels of estrogen receptor(ER) and Bcl-2 gene (Bcl-2). Methods: From December 2016 to December 2018, 100 women with uterine myoma were included and divided into two groups based on different treatments. The women in the control group were treated with laparoscopic hysteromyomectomy, and the women in the observation group were given HIFU treatment. The clinical effect of the women in the two groups after treatment was analyzed. Results: The recovery time of voluntary activity (0.6±0.2d), hospitalization time (4.5±1.1d), and blood loss (0ml) of the women in the observation group were significant lower than those of the women in the control group (P<0.05). There were no significant differences in the levels of anti-Mushi tube hormone (AMH), follicle stimulating hormone(FSH), luteinizing hormone (LH), and estradiol(E2) of the women between the two groups (P>0.05). The positive expression of ER and Bcl-2 of the women had decreased significantly after operation (P<0.05), but which had no significant differences of the women between the two groups (P>0.05). The complication rate of the women in the observation group (36.0%) was significant lower than that (56.0%) of the women in the control group (P<0.05). Conclusion: HIFU used for treating women with uterine myoma has little influence on their ovarian function with the characteristics of less trauma, rapid recovery, and high safety.
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