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| Analysis of the relationship of the abnormal blood glucose level of elderly pregnant women with gestational diabetes mellitus and their delivery outcomes and neonatal neurodevelopment |
| The Ninth Hospital of Xingtai City, Julu County, Hebei Province, 055250 |
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Abstract To explore the relationship of the abnormal blood glucose levels of elderly pregnant women with gestational diabetes mellitus (GDM) and their delivery outcomes and neonatal neurodevelopment. Methods: 186 elderly pregnant women with GDM were selected from October 2016 to September 2019. Based on 75 g oral glucose tolerance test (OGTT), these women were divided into three groups, which included group A (the women with one abnormal blood glucose result after OGTT), group B (the women with two abnormal blood glucose results after OGTT), and group C (the women with three abnormal blood glucose results after OGTT). 50 elderly pregnant women with normal blood glucose level were selected in control group during the same period. The delivery outcomes and neonatal neurological development score were compared among these groups. Results: The incidences of cesarean section, premature delivery, and macrosomia of the women in group A, B and C had increased in turn, and which were all significant higher than that of the women in the control group (P<0.05). The neonatal neurodevelopment score of the women in group A, B and C had decreased in turn, and which were all significant lower than that of the women in the control group (P<0.05). The incidences of cesarean section (47.6%), premature delivery (7.9%) and macrosomia (6.4%) of the women with good blood glucose control during pregnancy were significant lower than those (70.0%, 21.7%, and 20.0%) of the women with poor blood glucose control during pregnancy, but the neonatal neurodevelopment score (38.95±2.25 points) of the women with good blood glucose control during pregnancy was significant higher than that (35.85±1.12 points) of the women with poor blood glucose control during pregnancy (P<0.05). Conclusion: The higher the number of abnormal blood glucose items of elderly pregnant women with GDM, the higher the incidence of adverse birth outcomes and the more severely injure of the neurological development of newborns. Elderly pregnant women with GDM with good blood glucose control during pregnancy have better delivery outcomes and better neurological development of their newborns.
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