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| Relationship between the ultrasonic fetal aortic isthmus systolic index and the their prognosis in women with hypertensive disorder complicating pregnancy |
| The People's Hospital of Pudong New Area, Shanghai, 200120 |
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Abstract To analyze the significance of the fetal aortic isthmus systolic index (ISI) examined by ultrasound and its relationship with the fetal prognosis of pregnant women with hypertensive disorder complicating pregnancy (HDCP). Methods: 120 pregnant women with HDCP were selected and were divided in group A (63 cases with HDCP), group B (34 cases with mild preeclampsia), and group C (23 cases with severe preeclampsia) from January 2019 to March 2020. 60 normal pregnant women were selected in control group during the same period. The peak systolic velocity (PSV) and systolic nadir (NS) of the fetal aortic isthmus in the four groups were measured by ultrasound, and the prognosis of perinatal infants was recorded. Results: The values of PSV and NS of fetal aortic isthmus in group B and C were significant lower than those of fetal aortic isthmus in the control group (P<0.05), but which had no significant difference between the control group and group A (P>0.05). The values of PSV and NS of aortic isthmus of fetuses with good prognosis were significant higher than those of fetuses with poor prognosis (P&<0.05). Spearman analysis showed that PSV value of fetal aortic isthmus was negatively correlated with the fetal prognosis (rs=-0.801, P=0.017), but the NS and other ISI values were positively correlated with the fetal prognosis (rs=0.796, 0.805, P=0.022, 0.011). Conclusion: The decrease of fetal ISI of aortic isthmus value of the women with HDCP, especially the women with preeclampsia, is related to the fetal prognosis, so which can be used as a reference indicator for evaluating fetal prognosis. The significant decrease of fetal ISI value indicates the abnormal fetal hemodynamic changes and the increased risk of fetal adverse prognosis, which should be paid more attention to in clinical practice.
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