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| Effect of carprost ambutritol combined with uterine gauze packing for treating women with postpartum hemorrhage because of uterine weakness |
| Langfang People's Hospital, Hebei Province, 065000 |
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Abstract To investigate the effect of carprost ambutritol combined with uterine gauze packing for treating women with postpartum hemorrhage because of uterine weakness. Methods: The clinical data of 86 women with postpartum hemorrhage from May 2015 to May 2017 were collected. The women were divided into two groups according to different treatment methods. The women in the control group were treated with carprost ambutritol solution, and the women in the study group were treated with carprost ambutritol solution combined with uterine gauze packing. The amount of blood loss, the time of successful hemostasis, and the menstrual recovery situation of the women after intervention were compared between the two groups. The levels of anti-mullerian tubule hormone (AMH), estradiol (E2), and follicle stimulating hormone（FSH) of the women before and after treatment were compared between the two groups. And the pregnancy outcomes of the women after intervention were also compared between the two groups. Results: The blood loss (351.4±98.5 ml) in 2h after treatment or (105.6±12.3 ml) in 12h after treatment of the women in the study group was significantly lower than that (468.2±152.4 ml or 246.8±10.5 ml) of the women in the control group. The time of successful hemostasis (7.1±0.5h) of the women in the study group was significantly lower than that (12.3±2.6h) of the women in the control group (all P<0.05). Postpartum menstrual recovery, the levels of AMH, E2, and FSH, the situation of pregnancy again, and the situations of full term live birth, premature delivery, and spontaneous abortion of the pregnancy again of the women had no significant different between the two groups (all P>0.05). Conclusion: The application of carprost ambutritol solution combined with uterine gauze packing for treating women with postpartum hemorrhage because of uterine weakness can significantly shorten the time of successful hemostasis and can reduce their amount of blood loss, and which will not influence the postpartum menstrual recovery, ovarian function, and pregnancy again of the women.
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