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| The influence of different methods for treating infertile patients with hydrosalpinx on their ovarian reserve function and the pregnancy outcomes after IVF-ET |
| The First People’s Hospital of Zigong，Sichuan Province, 643000 |
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Abstract To explore the influence of different methods for treating infertile patients with hydrosalpinx on their ovarian reserve function and the pregnancy outcomes after IVF-ET. Methods: 171 infertility patients between March 2018 and May 2019 were analyzed retrospectively. These patients were divided into three groups according to the surgical methods. Among these patients, 58 cases in group A were treated by proximal tubal ligation combined with distal end tubal salpingostomy, 56 cases in group B were treated with salpingostomy, and 57 cases in group C were treated with salpingectomy. The ovarian reserve function, the ovarian volume, the total Gn dosage, the endometrial thickness, the time of Gn used, and the assisted pregnancy outcomes of the patients were compared among the three groups. The incidence of complications of the patients in the three groups during hospitalization was counted. Results: There were no significant differences in the levels of follicle stimulating hormone (FSH), estradiol (E2), and luteinizing hormone (LH), and the number of sinus follicles of the patients after treatment between group A and group B (P>0.05). In the 1st and 3rd menstrual cycle after treatment, the FSH and E2 levels of the patients in group A and group B were significantly lower than those of the patients in group C, but the LH level and the number of sinus follicles of the patients in group A and group B were significantly higher (all P<0.05). The ovarian volume (5.41±1.25 ml) of the patients in group A was significantly lower than that of the patients in group B or group C. The fertilization rate, the high-quality embryo rate, the clinical pregnancy rate, and the live birth rate of the patients were significantly higher than those of the patients in group B and group C. The complication rate (3.5%) of the patients in group A was significantly lower than that (14.0%) of the patients in group C (all P<0.05). Conclusion: Compared with that of the salpingectomy, the proximal tubal ligation combined with distal end tubal salpingostomy, and the salpingostomy for treating infertile patients with hydrosalpinx have less adverse influence on their ovarian reserve function. The proximal tubal ligation combined with distal end tubal salpingostomy also can increase the assisted pregnancy rate of the patients.
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