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| Diagnostic value of ultrasound imaging indexes combined with the levels of serum alpha fetal protein and creatine kinase for placenta previa complicated with placental implantation |
| Tianchang People's Hospital, Anhui Province, 239300 |
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Abstract To analyze the value of ultrasound imaging indexes combined with the levels of serum alpha fetal protein (AFP) and creatine kinase (CK) for placenta previa complicated with placental implantation. Methods: Pregnant women diagnosed with placenta previa by obstetric ultrasound were selected as the research subjects from March 2018 to December 2020. These women were divided into group A (the women with placental implantation disease) and group B (the women without placental implantation disease) according to whether the occurrence of placental implantation. The women in group A were further divided into group A1 (the women with placental adhesion) and group A2 (the women with confirmed placental implantation) according to the depth of villus invasion of the women. The women in these groups were given ultrasound examination and the serum AFP and CK detections. The women in group A were scored by ultrasound. Results: The serum AFP and CK levels of the women in group A were significantly higher than those of the women in group B, and the serum AFP and CK levels and the ultrasonic score of the women in group A1 were significantly lower than those of the women in group A2 (all P＜0.05). The serum AFP and CK levels had predictive value for placental implantation, which optimal cut-off value were 233.74ng/ mL and 153.26U/ mL, respectively. The serum AFP and CK levels and the ultrasound score of the women had predictive value for placental implantation type, which best cutoff values were 233.74ng/ ml, 153.26U/ml, and 8.49 points, respectively. The consistency of the serum AFP level, the CK level, or ultrasound examination alone for diagnosing placental implantation was common, and the consistency of the combined diagnosis of the serum AFP level, the CK level, and ultrasound examination for diagnosing placental implantation was better. The consistency of the serum AFP level, the CK level, or ultrasound examination alone for diagnosing placental implantation type was better, and the consistency of the combined diagnosis of the serum AFP level, the CK level, and ultrasound examination for diagnosing placental implantation type was perfect. Conclusion: Ultrasonography examination combined with the serum AFP and CK levels has good diagnostic efficacy for the placenta previa and placental implantation disease, and the placental implantation type, which can provide reference for the prenatal diagnosis of the pregnant women with placenta previa complicated with placental implantation.
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