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| Curative effect of Guchongsicao decoction combined with low molecular weight heparin sodium for treating the complications of uterine artery embolization and its influence on their serum C-reactive protein and interleukin-6 levels |
| Qingdao Jiaozhou Central Hospital, Shandong Province，266300 |
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Abstract To explore the curative effect of Guchongsicao decoction combined with low molecular weight heparin sodium for treating the complications of the women after uterine artery embolization and its influence on their serum C-reactive protein(CRP) and interleukin-6(IL-6) levels. Methods: 60 women with postpartum hemorrhage were divided into experimental group(30 cases) and control group(30 cases) according to different treatment methods from May 2018 to September 2020. The women in the control group had received uterine artery embolization combined with low molecular weight heparin sodium for treating postpartum hemorrhage, and the women in the experimental group had received Guchongsicao decoction for treating postpartum hemorrhage except to the treatment of uterine artery embolization combined with low molecular weight heparin sodium. The postpartum vaginal bleeding volume in 24 hours and complications rate, clinical efficacy, serum CRP and IL-6 levels, and symptom improvement situation of the women were compared between the two groups. Results: After treatment, the postpartum vaginal bleeding in 24h of the women in the experimental group was significantly less than that in the control group, and the total incidence of complication(10.0%), such as amenorrhea, menorrhagia, and post-embolization syndrome of the women in the experimental group was significantly lower than that(36.7%) of the women in the control group. The total effective rate(93.3%) of the women in the experimental group was significantly higher than that(70.0%) of the women in the control group. The serum CRP and IL-6 levels, and TCM syndrome score of the women in the two groups had decreased after treatment, and which of the women in the experimental group were significantly lower than those of the women in the control group(all P<0.05). Conclusion: Guchongsicao decoction combined with low molecular weight heparin sodium used for the women with postpartum hemorrhage can effectively reduce the incidence of complications of their uterine artery embolization, can improve their clinical efficacy, can reduce their inflammatory reaction, and can improve their clinical symptoms.
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