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| Effect of glucocorticoid combined with norade for treating women with endometriosis after laparoscopic surgery and its influence on their estrogen level and subsequent pregnancy |
| Wuxi Matemity and Child Health Care Hospital Affiliated to Nanjing Medical University，Wuxi, Jiangsu Province，214000 |
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Abstract To explore glucocorticoid combined with norade for treating women with endometriosis（EMT) after laparoscopic surgery, and to study its influence on their estrogen level and latter pregnancy. Methods: 100 women with EMT were selected and divided into control group and observation group（50 cases in each group) according to the random number table method from May 2018 to may 2019. The women in the control group were treated with norade after laparoscopic surgery for 6 months, and the women in the observation group were treated with glucocorticoid combined with norade for 6 months. The clinical efficacy, estrogen level, pregnancy rate, and recurrence rate of EMT of the women were compared between the two groups. Results: The total clinical effective rate(96.0%) of the women in the observation group was significantly higher than that(80.0%) of the women in control group(P<0.05). After treatment, the estrogen level of the women in both groups had decreased significantly, and the decreasing degree of the women in the observation group was significantly more than that of the women in the control group(P<0.05). The pregnancy rate(74.0%) of the women within 1 year after operation in the observation group was significantly higher than that(52.0%) of the women in the control group, but the recurrence rate of EMT(2.0%) of the women within 1 year after operation in the observation group was significantly lower than that(10.0%) of the women in the control group(P<0.05). Conclusion: Glucocorticoid combined with norade for treating women with EMT after laparoscopic surgery can not only significantly improve the clinical efficacy and estrogen level, but also can increase the latter pregnancy rate and can reduce the recurrence rate of EMT.
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