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| Characteristics of the current pregnancy in 205 women with preeclampsia history |
| 1.Wenzhou Central Hospital, Wenzhou, Zhejiang Province,325000；2.Obstetrics and Gynecology Hospital affiliate to School of Medicine, Zhejiang University |
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Abstract To evaluate the characteristics of pregnancy again of women with preeclampsia history, and to study the risks factors of recurrent preeclampsia. Methods: A retrospective study was performed on the clinical data of 205 pregnant women with preeclampsia history from January 2010 to December 2019. Results: There were 75 (36.6%) women with preeclampsia recurred in 205 women. Univariate analysis showed that obesity, advanced age, severe preeclampsia, early onset preeclampsia, and HELLP syndrome during previous pregnancy were associated with the recurrence of preeclampsia. Logistic regression analysis showed that obesity, advanced age, and early onset preeclampsia during previous pregnancy were the risk factors of the recurrence of preeclampsia. And low-dose aspirin could prevent recurrence of preeclampsia (P＜0.05). Low molecular weight heparin combined with aspirin had prolonged the gestational weeks and increased the birth weight of newborns when compared with aspirin or low molecular weight heparin used alone (P＜0.05). Conclusion: The effective monitoring and preventive measures should be conducted in pregnant women with obese, advance age, or history of early-onset preeclampsia for avoiding recurrent preeclampsia. Aspirin combined with low-molecular-weight heparin can prolong the gestational weeks and improve neonatal birth weight.
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