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| Analysis of the changes of serum of sex hormone and risk factors of women with recurrent ectopic pregnancy |
| 1. Nanjing Medical University, Jiangsu Province, 210000；2. Jiangyin people's Hospital；3. Suzhou Hospital Affiliated to Nanjing Medical University |
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Abstract To investigate the changes of serum of sex hormone and the risk factors of the women with recurrent ectopic pregnancy. Methods: 115 pregnant women with a history of ectopic pregnancy abortion were collected retrospectively. According to the pregnancy outcomes, 60 women with the second ectopic pregnancy were in group A, and 55 normal pregnant women were in group B. Logistic analysis was used to analyze the possible influencing factors of the second ectopic pregnancy. Results: The levels of human chorionic gonadotropin (HCG) and progesterone (P) of the women in group A during 6 gestational weeks were 5314.8±250.2 mIU/mL and 31.5±2.6 ng/mL, which were significant higher than those (1628.0±109.6 mIU/mL and 13.8±1.3 ng/ml) of the women in group B (P＜0.05). Logistic multiple regression analysis showed that the HCG level >2000 mIU/ml during 6 gestational weeks, the diameter of mass >4cm, the severe pelvic adhesion, and the poor tubal patency of lesion side of the women were the risk factors of their recurrent ectopic pregnancy (OR>1, P＜0.05), while the P level of the women was not the risk factors of their recurrent ectopic pregnancy. Conclusion: The HCG level >2000 mIU/ml during 6 gestational weeks, the diameter of mass >4cm, the severe pelvic adhesion, and the poor tubal patency of lesion side of the women were the risk factors of their recurrent ectopic pregnancy, so attention should be paid to and targeted preventive measures should be taken for reducing the recurrence of ectopic pregnancy in clinic.
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