Abstract To explore the clinical characteristics of atypical preeclampsia, and to analyz its risk factors. Methods: 268 pregnant women were divided into group A (women with atypical preeclampsia), group B (women with mild preeclampsia group B1 and women with severe preeclampsia in group B2) and group C. The clinical data of women in the three groups were analyzed. Results: The age and the serum levels of creatinine, uric acid and urinary protein of women in group A were significant higher than those of women in group C, but the delivery gestational weeks of women in group A was significant lower (P<0.05). There was no statistical significant difference in the SP and DP values between group A and C (P>0.05). The delivery gestational weeks when labor and the serum levels of creatinine, uric acid and urinary protein of women in group A and B1 were significant lower than those of women in group C (P<0.05), but those of women in group A had no significant different to those of women in group B1(P>0.05). The incidences of cesarean section, HELLP syndrome, thrombocytopenia, postpartum hemorrhage, anemia, and retinopathy of women in group A and group B1 were significant higher than those of women in group C, but which were significant lower than those of women in group B2 (P<0.05). There were no significant difference in the incidences of cesarean section, HELLP syndrome, thrombocytopenia, postpartum hemorrhage, anemia, and retinopathy between group A and group B1 (P>0.05). There were no significant difference in cesarean section rate and incidence of postpartum hemorrhage between group A and group B1 and group B2 (P>0.05). The proportions of women with aged ≥35 years old, with BMI <18.5kg/m2 or ≥24 kg/m2 during the first trimester of pregnancy, with a history of adverse pregnancy, without taken vitamins regularly during pregnancy, and with excessive weight gain during pregnancy in group A were significant higher than those in group C (P<0.05). The women with aged ≥35 years old, with with BMI <18.5kg/m2 or ≥24 kg/m2 during the first trimester of pregnancy, and with a dverse pregnancy history were independent risk factor for atypical preeclampsia (P<0.05). Conclusion: The incidences of injury and adverse pregnancy outcomes of women with atypical preeclampsia are similar to those of women with mild typical preeclampsia. The advanced age, too thin or overweight during the first trimester of pregnancy, and adverse pregnancy history are the independent risk factors of atypical preeclampsia.
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