|
|
|
| Influence of microdissection of testicular sperm extraction on complications and sperm acquisition rate of patients with non-obstructive azoospermia |
1.Hebei Research Institute of Family Planning Science and Technology, Shijiazhuang, Hebei Province, 05000；
2. Bethune International Peace Hospital |
|
|
|
|
Abstract To study the influence of microdissection of testicular sperm extraction (MD-TESE) on the complications and sperm acquisition rate of patients with nonobstructive azoospermia. Methods: 100 patients with non-obstructive azoospermia were selected and were divided into TESE group and MD-TESE group according to the operation methods (50 cases in each group) from May 2017 to May 2019. Radioimmunoassay was used to detect the levels of total testosterone (T), FSH and LH of all patients before and after operation. The erectile function and psychological evaluation of all patients were conducted, and sperm acquisition rate and the incidence of complications were analyzed. Results: The levels of T and LH of patients in both groups after operation had decreased significantly, but the FSH level had increased significantly, and the changes of the levels of T, LH and FSH of the patients in MD-TESE group were significant lower than those of women in TESE group. The IIEF-5 scores of the patients in the two groups after operation had increased significantly, but that of the patients in MD-TESE group was significant higher than that of women in TESE group (P<0.05). The postoperative sperm acquisition rate of the patients in MD-TESE group was 48.0%, which was significant higher than that (28.0%) of the patients in TESE group (P<0.05). The postoperative depression and anxiety score of the patients in TESE group had decreased significantly, but that of the patients in MD-TESE group had no changed significantly (P>0.05), and the postoperative depression and anxiety score of the patients in MD-TESE group was significant lower than that of the patients in TESE group (P<0.05). The incidence of complications of the patients in MD-TESE group was 4.0%, which was significant lower than that (18.0%) of the patients in TESE group (P<0.05). Conclusion: MD-TESE can reduce the postoperative complications of patients with non-obstructive azoospermia, improve their rate of sperm acquisition, and have little adverse effect on sexual function and psychological status of patients.
|
|
|
|
|
|
|
|
|
