Abstract Objective: The number of multiple gestations and adverse pregnancy outcomes have substantially increase, which primarily relate to a more wide use of assisted reproduction techniques. In the latest twenty years, multifetal pregnancy reduction has become a remedial measure to lessen maternal morbidity and fetal mortality by reducing the number of fetuses. However, due to the complexity of multiple pregnancies, the difference of chorionicity, the initial number of fetuses, especially the rise of high risk pregnant women after two-child policy, there are some disputes in the appropriate technique, the ideal timing of multifetal pregnancy reduction, and further pregnant management to perform selective termination. The purpose of this study was to review the method and timing of multifetal pregnancy reduction according to chorionicity and the initial number of fetuses.
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