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| Effect of curettage after bilateral uterine artery embolism or vaginal uterine scar pregnancy lesion removal combined with uterine repaired on quality of life of patients with uterine scar pregnancy |
| Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu Province, 210000 |
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Abstract Objective: To investigate the effect curettage after bilateral uterine artery embolism (UAE) or vaginal uterine scar pregnancy lesion removal combined with uterine repaired on quality of life of patients with uterine scar pregnancy. Methods: From March 2017 to May 2018, 61 patients with uterine scar pregnancy were enrolled in this study. Based on the principle of randomized controlled trial (RCT) and the willingness patients, these patients were divided into group A (26 women were given curettage after bilateral UAE) and group B (35 women were given vaginal uterine scar pregnancy lesion removal combined with uterine repaired). The operation situation, serum level of β-human chorionic gonadotropin (β-hCG), time ofβ-hCG returned negative, menstrual recovered time of women were compared between the two groups. The postoperative quality of life of patients was evaluated by World Health Organization Quality of Life scale (WHOQOL-BREF). Results: The operation time and blood loss of women in group A were significant lower than those of women in group B, but the vaginal bleeding time, hospitalization time after operation, and costs of treatment of women in group A were significant higher (all P<0.05). The degree of serum β-hCG level decreased of women 24 h after operation in group B was better than that of women in group A (P<0.05). The negative conversion time ofβ-hCG, the time of menstruation recover, and the related to physiological and social scores 3 months after operation of women in group A were significant less than those of women in group B (all P<0.05). There were no significant difference in psychology environmental domain score of women 3 months after operation and WHOQOL-BREF score 6 months after operation between the two groups. Conclusion: Curettage after bilateral UAE for treating uterine scar pregnancy has the same effective of vaginal uterine scar pregnancy lesion removal combined with uterine repaired, both can preserve the fertility function with high safety. The treatment time of vaginal uterine scar pregnancy lesion
removal combined with uterine repaired is short and the cost is low, but curettage after bilateral has a slight advantage in the choice of repregnancy time and the improvement of quality of life after operation.
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