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| Study on the association between the history of inducde abortion of reproductive-age women and their time to pregnancy |
| 1. National Research Institute for Family Planning, Beijing, 100081；2. Graduate School of Peking Union Medical College；3. Shenzhen Health Development Research Center |
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Abstract Objective: To explore the association between the history of inducde abortion of reproductive-age women and their time to pregnancy (TTP). Methods: A retrospective cohort study was conducted in 44 672 eligible reproductive-age women who participated in the National Free Preconception Checkup Projects in Shenzhen from January 2013 to December 2017. A total of 20,608 women with a history of artificial abortion were selected in the exposed group (including 14,762 women with a history of one abortion and 5,846 women with a history of two or more abortions), while 24,064 women without history of abortion were selected in the non-exposed group. The χ2 test was used to compare the baseline characteristics of women between the two groups, Kaplan-Meier method was used to calculate the cumulative pregnancy rate for each menstrual cycle, and Cox model was used to estimate the influence of artificial abortion history of reproductive-age women on their TTP. Results: The cumulative pregnancy rate in 12 menstrual cycles of reproductive-age women in the non-exposed group was 32.6%, which was significant lower than that (38.9%) of women with a history of one abortion or that (34.0%) of women with a history of more than once abortions. After adjusting the influencing factors, compared with reproductive-age women with no history of abortion, women with a history of one or more than once obortion had a increased fertility of 19.0% (FOR=1.190, 95% CI: 1.147-1.234) and 21.5% (FOR=1.215, 95% CI: 1.153-1.280) , respectively. Conclusion: Reproductive-age women with a history of artificial abortion have higher fertility ablity and their TTP is not prolonged. In view of this specific population with higher fertility, scientific contraceptive guidance should be done to avoid the adverse effects of repeated induced abortions after multiple unplanned pregnancies on their reproductive health.
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| [1] |
LI Jiaheng, LI Yijiang, LI Mengnuo, ZHAO Xianling, GUAN Yichun, LIU Yanli, JIA Qi, LI Jing, DU Shanshan, LV Yidong. Investigation and research on the cognition of the fertility preservation of the oncology and reproductive related physicians and the patients with cancer[J]. 中国计划生育学杂志, 2024, 32(5): 1009-. |
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