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Abstract Objective: To explore the influence of vaginal microbes on group B streptococcus (GBS) infection of pregnant women during the third trimester of pregnancy. Methods: 80 pregnant women during the third trimester of pregnancy were selected as research objects from August 2014 to May 2018, and their vaginal secretions were collected for detecting B streptococcal infection. 24 women with positive B streptococcal infection were in study group A, and 56 women with negative B streptococcal infection were in control group. The influence of vaginal microbes of women in both groups on their vaginal GBS infection was studied. Results: The abnormal vaginal PH rate of women in the study group was 91.7%, which was significant higher than that of women in the control group. The rates of fungus positive and bacterial vaginosis positive of women in the study group were 25.0% and 33.3%, which were significant higher than those (4.0% and 7.8%) of women in the control group (P<0.05). There was no significant different in trichomonas positive rate of women between the two groups (P>0.05). The positive rates of hydrogen peroxide (H2O2), leucocyte esterase (LE), sialidase (SnaSe), proline aminopeptidase (PIP), acetylaminoglucosidase (NAG) of women in the study group were significant higher than those of women in the control group (P<0.05 ). Conclusion: The vaginal microbes of pregnant women during the third trimester of pregnancy have some influence on their GBS infection, so the detection of vaginal microflora should be paid more attention to.
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