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| Aralesic efficacy of propofol for painless induced abortion |
| 1. Key Laboratory of Anesthesiology of Xuzhou Medical University, Xuzhou, Jiangsu Province, 221009；2. The Second Hospital of Wuxi；3. Wuxi People's Hospital |
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Abstract Objective: To investigate the effect and adverse reaction of propofol combined with butorphanol used for painless artificial abortion. Methods: 2000 women who underwent painless abortion were enrolled and were divided into two groups by the random number table from May to May 20, 2015. The women in the control group were given intravenous propofol, and the women in the study group were given intravenous propofol combined with butorphanol. The heart rate before and after operation, blood loss volum during operation, and operation time of women in both groups were observed. The analgesic effect and adverse reaction of women were compared between the two groups. Results: The analgesic effective rate of women in the study was 100.0%, which was significant higher than that (84.2%) of women in the control group (P<0.05). The heart rate and values of MAP and SpO2 of women in the study were significant better than those of of women in the control group (P<0.05). The operation time, the amount of bleeding during operation, and the incidence of adverse reaction of women in the study were 2.6±0.9min, 11.1±4.4ml, and 5.6%, respectively, which were ignificant higher than those (4.6±0.6min, 20.2±4.8ml, and 14.2%, respectively) of women in the control group (P<0.05). Conclusion: The efficacy of propofol combined with butorphanol used for painless artificial abortion is better than that of propofol used only, which has economic and convenient advantages, so it is worthy of application in clinical practice.
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