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Abstract To observe the differences of uterine artery blood flow and serological markers of pregnant women with uterine atony. Methods: 60 pregnant women with uterine atony were selected in study group from March to February 20-18, 216, and 60 normal pregnant women were selected in control group during the same period. The levels of placental growth factor (PLGF) and vascular endothelial growth factor-1 (VEGFR-1), sEng, and adiponectin of women were compared between the two groups. The correlation between uterine artery flow values and serological indicators of pregnant women with uterine contraction was analyzed. Results: The levels of S/D, RI and PI of women in the study group were 2.83±0.31, 1.21±0.22, and 0.78±0.15, respectively, which were significant higher than those (1.75±0.23, 0.68±0.17, and 0.37±0.11, respectively) of women in the control group (t=-21.672, -14.766, -17.073), but the levels of PLGF and PLGF/sEng of women in the study group were 225.29±12.98pg/ mL and 35.19±6.24, which were significant lower than those in the control group (P<0.001). The levels of sEng and adiponectin were 6.98±1.02pg/ml and 16.35±2.11 g/ml, which were significant higher than those of women in the control group (P<0.001). The value of uterine artery blood flow of pregnant women with uterine atony was negative correlated with PLGF and PLGF/sEng levels (r=-0.475, -0.484, -0.449, -0.475, 0.532, -0.398, P＜0.05), but was positive correlated with sEng and adiponectin levels (r=0.502, 0.573, 0.512, 0.527, 0.433, 0.423, P<0.05). Conclusion: The uterine artery blood flow value of pregnant women with uterine atony is high, which is closely related to serum PLGF, PLGF/sEng, sEng and adiponectin levels.
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