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| The clinical value of the levels of AMH, LH and T for diagnosing polycystic ovary syndrome and its relationship with insulin resistance |
| Xianning Center Hospital, Hubei Province, 437100 |
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Abstract To study the relationship between levels of anti-muller-tube hormone (AMH), luteinizing hormone (LH), testosterone (T), and their insulin resistance (IR) of women with polycystic ovary syndrome (PCOS), and to study their diagnostic value. Methods: 120 women with PCOS were selected in study group from February 2018 to December 2019, and another 120 women who had physical examination were selected in control group during the same period. The levels of AMH, LH, and T, and the value of IR of women in the two groups were detected, and their correlation was analyzed. The diagnostic efficiency of AMH, LH and T levels for PCOS was analyzed. Results: Serum levels of AMH, LH, and T, and IR value of women in the study group were significant higher than those of women in the control group, and the levels of AMH, LH, and T were positively correlated with IR value (all P＜0.05). The sensitivity of combined detection of levels of AMH, LH, and T for diagnosing PCOS was 80.7%, which was significant higher than that of single detection, but the detection accuracy and the specificity of combined detection of levels of AMH, LH, and T for diagnosing PCOS were 36.7% and 14.9%, which were significant lower than those of single detection. ROC curve analysis showed that the critical value of serum AMH level, LH level, or T level for diagnosing PCOS were 62.33 pmol/L, 12.11 pmol/L, and 1.81 pmol/L, respectively. Conclusion: The changes of the levels of AMH, LH and T for diagnosing PCOS were significantly correlated with IR value.
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