|
|
|
| The influence of preimplantation genetic screening on pregnancy outcomes of women with recurrent spontaneous abortion |
| Gansu Provincial Maternity and Child Health Care Hospital, Lanzhou, Gansu Province, 730050 |
|
|
|
|
Abstract Objective: To explore the influence of preimplantation genetic screening on pregnancy outcomes of women with recurrent spontaneous abortion. Methods: The women with recurrent spontaneous abortion were divided into the study group and the control group randomly, and women in the study group had received preimplantation genetic testing and the women in the control group had received routine IVF embryo transfer. The pregnancy outcomes of women were compared between the two groups. Results: A total of 212 embryos of women in the study group were biopsied after 40 treatment cycles, which included 115 (54.2%) euploid embryos and 97 (45.8%) aneuploid embryos. The embryo implantation rate and clinical pregnancy rate of women in the study group were 68.8% and 68.6%, which were significant higher than those (35.3% and 52.8%) of women in the control group, the early abortion rate of women in the study group was 12.5%, which was significant lower than that (26.3%) of women in the control group (P<0.05). Conclusion: The selection of aneuploidy embryo transfer after preimplantation genetic screening for treating women with recurrent abortion can improve the implantation rate and clinical pregnancy rate, and can reduce early abortion.
|
|
|
|
|
|
|
|
|
