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| The Investigation of influencing factors of vitamin A levels of pregnant women |
| 1.North Hospital Affiliated to Xi 'an Medical College of Xi’an, Shaanxi province, 710043；2. Shaanxi Provincial People's Hospital |
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Abstract Objective: To explore the changes and influencing factors of vitamin A (VA) of pregnant women during pregnancy, and to provide evidences for rational VA nutrition treatment. Methods: A total of 5104 pregnant women who accepted antenatal check-ups were selected to finish the questionnaires from April 2015 to February 2017, and their serum samples during different pregnant periods were collected and detected for knowing their VA levels. Results: The proportion of abnormal serum VA level of the pregnant women was 10.7%, which included VA deficiency accounted for 9.7% and VA excess accounted for 1.0%. The proportion of VA deficiency of women during the third trimester pregnancy was high (18.5%). The single risk factor of VA deficiency of women during the first trimester pregnancy was pregnancy vomiting, threatened abortion, history of infectious gastroenteritis, or partial eclipse. The single risk factor of VA deficiency of women during the second trimester pregnancy was gestational diabetes, intake related foods (animal liver, milk and broccoli, etc.), or oral related drugs. The single risk factor of VA deficiency of women during the third trimester pregnancy was body mass index, anemia, gestational diabetes, hypertensive disorders during pregnancy, or partial eclipse. Multivariate logistic regression showed that the risk factor for VA deficiency during the first and third trimester pregnancy was partial eclipse, and the risk factors during the second trimester pregnancy were taken related foods and drugs (P<0.05). Conclusion: The VA level of pregnant women has differences during different trimester pregnancy, and VA deficiency is common in pregnant women, so VA reasonable supplements is benefit for maternal and child safety.
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