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| The effect of dinoprostone and oxytocin for improving cervical maturity of pregnant women when induced labor during the third trimester and its influence on maternal and infant outcomes |
| Anyang Maternal and Child Health Care Hospital, Henan Province, 455000 |
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Abstract Objective: To analyze the effect of dinoprostone and oxytocin for improving cervical maturity of pregnant women when induced labor during the third trimester. Methods: 250 pregnant women accepted labor induction during the third trimester pregnancy were randomly divided into the observation group (n=125, dinoprostone used for improving cervical maturity) and the control group (n=125, oxytocin used for improving cervical maturity) from April 2015 to January 2018. The efficacy of cervical maturation promotion by cervical Bishop score, efficacy of induction of labor, delivery situation, postpartum outcomes, and neonatal status of all included women were recorded. Results: Bishop scores of women in the observation group at 6h and 12h after cervical maturation promotion were significant higher than those of women in the control group (P<0.05). The total effective rate of induced labor of women in the observation group was 89.6%, which was significant higher than that (79.2%) of women in the control group, vaginal bleeding time, the time from cervical maturation promotion to labor, total labor time of women in the observation group were significant shorter than those of women in the control group, the rate of vaginal delivery of women in the observation group was 83.2%, which was significant higher than that (67.2%) of women in the control group (P<0.05). The volume of blood loss in postpartum 24h, and the intrauterine residual rate, and the time of menstruation recovery of women, and the rates of fetal distress and neonatal asphyxia in the observation group were significant lower than those of women in the control group (P<0.05), neonatal Apgar scores in the observation group was significant higher (P<0.05), but there was no difference in the rate of puerperal infection and cervical laceration of women between the two groups (P>0.05). Conclusion: Compared with oxytocin, dinoprostone used for improving cervical maturity of women when induced labor can shorten the time of vaginal bleeding and menstruation recovery, and can improve the success rate of induced labor and the maternal and infant outcomes.
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