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| The effects of dexmedetomidine on postoperative pain and sleep quality of elderly women undergone hysteromyomectomy based on general anesthesia |
| Taizhou Central Hospital, Zhejiang Province, 318000 |
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Abstract Objective: To analyze the effects of dexmedetomidine on postoperative pain and sleep quality of elderly women undergone hysteromyomectomy based on general anesthesia. Methods: 92 elderly women undergone hysteromyomectomy based on general anesthesia were randomly divided into the observation group and the control group (46 cases in each group) from June 2016 to June 2017. After operation, the women in the observation group were given dexmedetomidine combined with sufentanil for analgesia, while the women in the control group were given sufentanil for analgesia only. The pain degree of women evaluated by visual analogue scale (VAS) at 1h, 6h, 12h, 24h and 48h after analgesia, the number of effective pressing analgesic pump in 0-12h, 12-24h, 24-36h and 36-48h after analgesia, the changes of heart rate (HR), blood oxygen saturation (SpO2), blood pressure (BP), and the incidences of adverse reactions such as nausea and vomiting during the analgesia process were compared between the two groups. Medical outcome study sleep scale (MOS-SS) was used to evaluating the preoperative and postoperative sleep quality and the postoperative sleep satisfaction of all women. Results: The VAS scores of women at 1h, 6h, 12h, 24h and 48h after analgesia in the observation group were significant lower than those of women in the control group (P<0.05). The number of effective pressing analgesia pump by women in the observation group was significant less than that in the control group at 0-12h, 12-24h, 24-36h and 36-48h after analgesia (P<0.05). The incidences of adverse reactions and MOS-SS scores of women at 4 weeks after operation in the observation group were significant lower than those of women in the control group (P<0.05), and the sleep satisfaction degree was significant higher than that of women in the control group (P<0.05). Conclusion: Compared with that of sufentanil used alone for postoperative analgesia, dexmedetomidine combined with sufentanil can relieve postoperative pain, can improve sleep quality, and can reduce the incidence of adverse reactions of elderly women undergone hysteromyomectomy based on general anesthesia.
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