|
Abstract Objective: To establish the determination of octamethyl cyclotetrasiloxane (D4), decamethyl cyclopentasiloxane (D5) and dodecamethyl cyclohexasiloxane (D6) of silicone oil as lubricant of condoms by GC-MS．Methods：The D4, D5 and D6 were extracted by acetone, and separated by gas chromatography．The D4、D5 and D6 were confirmed by GC-MS, and their quantitative analysis were conducted by standard curve method．Results：The well linearity ranges of D4, D5 and D6 were 0.0953-19.0512μg/ml，0.0927-18.5328μg/ml, 0.0867-17.3436μg/ml, respectively. The average recovery rate of D4, D5 and D6 were 88.8%, 94.9% and 99.8%, respectively. The quantitative analysis of D4, D5 and D6 extracted from silicone oil of 26 condom samples made from different manufacturers were 0.33-733mg/g, 0.08-223.25mg/g, and 0-218.50 mg/g, respectively. Conclusion：This established method is proved by methodology, and GC-MS can be used for determining the amount of D4, D5 and D6 extracted from silicone oil of the condoms.
|
