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Application of two different treatment protocols for patients with poor ovarian response |
Union Hospital, Tongji Medical Colleage, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430022 |
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Abstract Objective: To explore the value of two different treatment protocols in vitro fertilization and embryo transfer (IVF-ET) of patients with poor ovarian response. Methods: A retrospective study about 355 cycles of patients with poor ovarian response who had received IVF-ET was conducted. The patients were divided into group A (GnRH-a long protocol) and group B (CC+Gn protocol). Results: The Gn days of patients in group A was significant lower than that of patients in group B (P<0.05). There were no significant different in the total fertility rate, high-quality embryo rate, and fresh cycle pregnancy rate between the two groups (P >0.05). The rates of total fertility, embryo quality, and fresh cycle pregnancy of patients in group A were significant lower than those of patients in group B (P<0.05), but rates of blastocyst formation and frozen-thaw cycle pregnancy of patients in group A were significant higher than those of patients in group B (P<0.05). Conclusion:The CC+Gn protocol is one of the effect protocols for treating patients with poor ovarian response.
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