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| A study of the situation of hepatitis B virus infected pregnant women in Chengdu City |
| Chengdu City Women’s and Children’s Central Hospital, Chengdu City, Sichuan Province, 610091 |
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Abstract Objective: To understand the current situation of hepatitis B virus (HBV) infected pregnant women in Chengdu City，and to provide scientific evidences for preventing and controlling mother-to-child transmission of HBV．Methods: 131507 blood samples of pregnant women were collected from 2012 to 2017，and the HBV levels were detected from these samples by enzyme-linked immunosorbent assay (ELISA). Results: The total positive rate of hepatitis B surface antigen (HBs Ag) was 7.39％ and the positive rates of HBs Ag in pregnant women had showed significantly decline year by year in Chengdu city from 2012 to 2017 (P＜0.05)．And the positive rate of HBs Ag gradually increased with the age increasing of pregnant women (P＜0.05)．There were 41737 cases (31.7%) whose HBs Ag and HBs Ab test results were both negative, and these pregnant women were susceptible to HBV infect in future. In women with HBV infected, there were two main infected models, which included 20.3% women with HBs Ag, HBe Ag and HBc Ab positive, and 69.1% women with HBs Ag, HBe Ab and HBc Ab positive. Conclusion: There is a certain percentage of pregnant women with HBV infected or susceptible infection in Chengdu City. So the monitoring of HBV infection and vaccination using in pregnant women should be strengthened to prevent mother-to-children transmission of HBV.
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