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| The application of compound zhicao decoction combined with methotrexate for conservative treatment of women with ectopic pregnancy |
| 1. Lishui City Maternal and Child Health Care Hospital, Zhejiang Province, 323000; 2. Lishui City Hospital of Traditional Chinese Medicine of Zhejiang Province |
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Abstract Objective: To observe the efficacy and safety of compound zhicao decoction combined with methotrexate (MTX) for conservative treatment of women with ectopic pregnancy. Methods: 80 women with ectopic pregnancy were randomly divided into group A and group B (40 cases in each group) from June to February 2018. The women in group B were treated by MTX only for 2 weeks, and women in group A were treated by compound Zhicao decoction combined with MTX for 2 weeks. The clinical efficacy, symptoms and signs disappearance time, and the rate of adverse reaction were observed. Results: The clinical effective rate of women in group A was 92.5%, which was significant higher than that (75.0%) of women in group B (P<0.05). The time ofβ-HCG level decreased to 50% or disappearance, and pelvic mass disappearance time of women in group A were significantly shorter than those of women in group B (P<0.05). The incidence of adverse reaction of women in group A during the treatment was 12.5%, which was significant lower than that (32.5%) of women in group B (P<0.05). Conclusion: Compound Zhicao decoction can significantly improve the cure rate of women with ectopic pregnancy, shorten the disappearance time of pelvic mass, and improve the recovery of women.
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