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Abstract To evaluate the prenatal diagnosis and prognosis of fetal respiratory dysplasia. Methods: 125 fetuses with respiratory system dysplasia diagnosed in prenatal diagnosis center of International Peace Maternity & Child Health Hospital during Jan.2015 and Dec.2017 were reviewed. Results: Among these fetuses, there were 103 cases with fetal cystic adenomatoid malformation (CCAM), 41 cases with fetal bronchopulmonary sequestration (BPS), and 8 cases with diaphragmatic hernia (CDH). The fetus with CCAM was the most common respiratory system dysplasia, and the number of fetus with CDH was gradually growing in recent years. The proportion of fetus with CCAM, BPS and CDH were 17.5%, 7.3% and 12.5%, respectively. One fetus with normal fetal karyotype had a VUS microarray result with unclear clinical significant. The induction rates of women because their fetus with CCAM, BPS and CDH were 8.7%, 7.3% and 12.5%, respectively. The healthy survival rate of the fetus with CCAM and BPS was higher, compared to fetus with CDH needed surgical after born. Conclusion: The norms and standards of ultrasound examination for fetal respiratory diseases, genetic counseling system, neonatal examination and follow-up system should be established systematically to obtain more reliable continuous evidence for improving the level of prenatal diagnosis and counseling for fetal respiratory diseases.
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