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| The value of fetal hemodynamic parameters by ultrasound for dignosing fetal distress caused by intrahepatic cholestasis during pregnancy |
| Qinghai Red Cross Hospital, Xining, Qinghai Province, 810000 |
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Abstract Objective: To investigate the value of fetal hemodynamic parameters by ultrasound for dignosing fetal distress caused by intrahepatic cholestasis during pregnancy (ICP). Methods: 100 normal pregnant women were selected in group A, and 200 pregnant women with ICP were were selected in group B (women with mild ICP) and in group C (women with severe ICP) from October 2017 to October 2018. The values of resistance index (RI), Pulsatility index (PI), and the ratio of systolic blood pressure and diastolic blood pressure (S/D) of UA and MCA of women were determined and compared among the three groups. The ROC curve was drawn by RI, PI and S/D of UA and MCA. Results: There was significant different in RI, PI and S/D of UA between the three groups. The value of RI, PI or S/D of UA of women in group C was the highest (P<0.05). The area under ROC curve of RI, PI or S/D of UA was over 0.7 (P<0.05). The sensitivity, specificity, and area under ROC curve of RI of UA were the highest. The value of RI, PI or S/D of MCA of women in group C was the highest (P<0.05). The area under ROC curve of RI, PI or S/D of MCA was over 0.8 (P<0.05). The sensitivity, specificity, and area under ROC curve of PI of UA were the highest. Conclusion: UA and MCA examination by ultrasound can be used for predicting fetal distress of women with ICP. The RI of UA and PI of MCA were more preferably used in clinical diagnose.
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