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| Application of combined spinal and epidural anesthesia in cesarean section of women with pregnancy induced hypertension and its influence on their hemodynamics and hemorheology |
| The First Affiliated Hospital of Xi’AN Jiao Tong University，Shaanxi Province,710061 |
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Abstract Objective: To study the effect of combined spinal and epidural anesthesia in cesarean section of women with pregnancy induced hypertension syndrome, and to expore its influence on hemodynamics and hemorheology of women. Methods: 87 women with pregnancy induced hypertension who experinced cesarean section were divided into observation group (41 cases) and control group (46 cases) from April 2017 to March 2018 according to simple randomization method. During cesarean section, continuous epidural anesthesia was used in the control group， and combined with spinal and epidural anesthesia was used in the observation group. The hemodynamics and hemorheology indicators of women and neonatal situation in both groups were analyzed. Results: The excellent rate of anesthesia of women in the observation group was 90.2%, which was significant higher than that (63.0%) of women in the control group (P<0.05). The anesthetic onset time, anesthetic dose, and VAS score of were women in the observation group were 3.4±0.4min, 1.4±0.2ml, and 2.8±0.3 score, respectively, which were significant lower than those (9.0±0.9min, 12.9±1.2ml, and 9.2±0.9 score, respectively) of women in the control group (P<0.05). After anesthesia, the heart index, acceleration index, value of left heart work, diastolic blood pressure, systolic blood pressure, heart rate, stroke index, and cardiac output of women in the observation group were significant lower than those of women in the control group (P<0.05). There was no significant difference in the Apgar score between the two groups (P>0.05). Conclusion: The combined spinal and epidural anesthesia can effectively stabilize hemodynamics and hemorheology of women with pregnancy induced hypertension during cesarean section. The anesthesia has a quick onset and better anesthesia efficacy with less anesthetic medicinal dose, which can alleviate the pain of women.
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