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| The relationship between the placental growth factor level and uterine arterial blood flow, gestational weeks, or newborn weight of pregnant women with early onset preeclampsia |
| Wenzhou City Integrated Hospital of Traditional Chinese Medicine and Western Medicine, Zhejiang Province, 325000 |
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Abstract To explore the correlation between the placental growth factor (PLGF) level and uterine arterial blood flow, gestational weeks, or newborn weight of pregnant women with early onset preeclampsia (EOPE). Methods: The pregnant women with EOPE were selected into study group, and normal pregnant women were selected into control group during the same time. The differences of serum PLGF level and uterine artery blood flow parameters were compared between the two groups. The relationship between the level of serum PLGF and uterine artery blood flow, the gestational weeks, or the newborn weight of women in study group was also analyzed. Results: The delivery gestational weeks, newborn birth weight and the level of serum PLGF of women in study group were significant lower than those of women in control group (P<0.001), but the S/D, RI and PI of uterine artery blood flow of women in study group were significant higher than that those of women in control group (P<0.05). In the study group, the level of serum PLGF was negatively correlated to the S/D, RI and PI values of uterine artery blood flow (r=-0.832,-0.366, -0.562,P<0.001) , but was positively correlated to the gestational weeks and the newborn weight (r=0.327,0.763,P<0.005). Conclusion: The level of serum PLGF of pregnant women is closely related to the occurrence of EOPE, which can be used as a reference indicator for predicting EOPE.
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