|
|
Clinical observation of tumor occurrence of infertile women after accepted different assisted reproductive technology |
Reproductive Center, Tianjin Medical University General Hospital,Tianjin, 300052 |
|
|
Abstract Objective: To investigate the incidence of malignant tumors of infertile women after vitro fertilizationembryo transfer (IVFET) or intrauterine insemination (IUI). Methods: A retrospective study was conducted among patients with assisted reproductive technology(IVF/ICSI group and IUI group) in the reproductive center of Tianjin medical university general hospital from January 1th, 1999 to December 31th,2015. The characteristics and the tumor incidences of included women were analyzed and compared between IVF/ICSI group and IUI group. Results: There were 13 women had been found malignant tumors in this study, which included 10 cases (0.6%) in IVF/ICSI group and 3 cases (0.8%) in IUI group. There was statistically significant differences between the two groups(χ2=0.33,P=0.48). The incidence of tumor in patients with longterm infertility (more than or equal to 5 years) was 1.3%, which was significant higher than that of patients with short term infertility (0.4%)(χ2=4.63,P=0.04). The incidence of tumor in older patients was significant higher than that in young patients (χ2=11.64,P=0.01). Conclusion: Compared to IUI, IVF/ICSI can not increase the incidence of tumor. The longterm infertility and elder age maybe high risk factors for malignant tumors.
|
|
|
|
|
|
|
|