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| Clinical value of hysteroscopy in women with recurrent implantation failure |
| The First Clinical Hospital of Peking University, Beijing, 100034 |
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Abstract Objective: To explore the influence of hysteroscopy operation on clinical outcome of patients with recurrent implantation failure (RIF). Methods: This retrospective cohort study analyzed the data of 118 patients with two or more failed IVFET cycles in the first clinical hospital of Peking university. The patients were divided into three groups based on hysteroscopy, which included that the women with normal uterine cavity and endometrial scratching were in group A (n=57), the women with Endometrial polyps were in group B1 (n=40), and the women with the other abnormal findings were in group B2 (n=21). The implantation rate and clinical pregnancy rate were compared among the three groups. Results: The incidence of abnormal uterine cavity in RIF patients discovered by hysteroscopy was 51.7%, the incidence of endometrial polyps was 65.6%, the others abnormal hysteroscopy findings was 34.4%. There was no significant difference in implantation rate and clinical pregnancy rate of women between group A and group B1（23.7% vs. 30.1%，P＞0.05；43.9% vs 55%，P＞0.050）, but the implantation rate (8.9%)and clinical pregnancy rate(14.3%) of women in group B2 were significant higher than those of women in group A and group B1（P=0.024,P=0.009）. Conclusion： The cavity and the tiny lesions of the cavity of patients with RIF can be observed clearly by hysteroscopy. The most common abnormal finding by hysteroscopy is endometrial polyps. The implantation rate and clinical pregnancy rate of women with endometrial polyps will significant higher than those of women with other abnormal hysteroscopy findings after the treatment by hysteroscopy.
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