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| Immunotherapy for unexplained recurrent spontaneous abortion |
| The First Hospital of Peking University, Beijing, 100034 |
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Abstract Various causes have been found to contribute to the pathogenesis of recurrent spontaneous abortion (RSA). Still about 50% of the RSA cases have no known etiology and are considered as unexplained recurrent spontaneous abortion (URSA). Though may treatments have been for URSA, but some of them remain controversial. URSA has been assumed to be caused by a defect in maternal immunological tolerance to the fetus, so researches on the immune disturbance and immunomodulatory treatments for URSA have become a hot topic in the field of reproduction recently. Evaluation of the therapeutic strategies for URSA in this review aims at providing evidence for facilitating clinical therapy.
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