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| Effects of vaginal placement of carboprost or misoprostol for cervical dilatation of patients underwent transcervical resection of submucosal myoma by hysteroscopic |
| Chongqing Women and Children Health Care Hospital, Chongqing, 400000 |
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Abstract Objective: To analyze the effect of vaginal placement of carboprost or misoprostol for cervical dilatation of patients underwent transcervical resection of submucosal myoma(TCRM) by hysteroscopic. Methods: A comparative study included 128 patients with subumcosal myoma of uterus (SMU) of type I who had admitted to Chongqing women and children health care hospital from June 2015 to June 2017. According to the different methods of preoperative cervical preconditioning, 128 patients were randomly divided into two groups (64 cases in each group). Before operation, the patients in carboprost group were given vaginal placement of carboprost, and the patients in misoprostol group were given vaginal placement of misoprostol. The degree of cervical dilatation and operation situation of patients were compared between the two groups. Results: The effect rate of cervical dilatation and total effective rate of patients in carboprost group were significant better than those of patients in misoprostol group (P<0.05), the operation time of patients in carboprost group was significant shorter than that of patients in misoprostol group (P<0.05), and the amount of bleeding of patients in carboprost group was significant lower than that of patients in misoprostol group (P<0.05), but there was no significant different in the rate of drug adverse reaction between the two groups (P>0.05). Conclusion: Vaginal placement of carboprost is beneficial to patients with SMU before hysteroscopic TCRM, which can reduce the amount of bleeding and shorten the operation time. And vaginal placement of carboprost is easy, safety and effective.
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