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| Study on effect of diffrent anesthetic in cesarean section of pregnant women with hepatitis cirrhosis |
| Third People's Hospital of Xining, Qinghai Province |
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Abstract Objective:To observe the effect of different anesthesia in cesarean section of pregnant women with hepatitis cirrhosis. Methods: From January 2015 to January 2018, 112 pregnant women with hepatitis cirrhosis who wanted to cesarean section were selected as the subjects, and were divided in two groups (56 cases in each group) according to the platelet count (PLT). The women in observation group (PLT>50×109/L) was given single lumbar anesthesia, and the women in control group (PLT<50×109/L) was given general anesthesia. The maternal and neonatal related indicators and liver function indicators were compared between the two groups, and the Apgar scores of newborns at 1 and 5min after birth in the two groups were analyzed. Results: Before anesthesia, there were no significant different in liver function indexes, operation time, valume of intraoperative blood loss, neonatal birth weight, hospitalization days between the two groups (P>0.05). After induction of anesthesia, the level of albumin of women in observation group was significant lower than that of women in control group (P<0.05). There was no significant difference in levels of alanine aminotransferase, total bilirubin and alkaline phosphatase between the two groups (P>0.05). Postoperation 1 day, the level of albumin of women in observation group was significant lower than that of women in control group. The level of alkaline phosphatase of women in observation group was significant higher than that of women in control group (P<0.05), but there was no significant different in the other indexs between the two groups (P>0.05). In 1 min after born, the incidence of severe asphyxia of newborns in observation group was significant lower than that of newborns in control group (P<0.05), but there was no different in the incidence of asphyxia of newborns in 5min after born between the two groups (P>0.05). Conclusion: In order to ensure the safety of mother and infant, diffrent anesthetic method during cesarean section of women with cirrhosis should be selected based on the actual situation of pregnant women.
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