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| The value of serum PSA, T and DHEAS levels for diagnosing of polycystic ovary syndrome#br# |
| 1. Graduate School of Xuzhou Medical University，Xuzhou, Jiangsu Province, 221004; 2. Affiliated Hospital of Xuzhou Medical University |
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Abstract Objective: To analyze the value of serum prostaglandinspecific antigen (PSA), testosterone (T) and DHEAS for diagnosing women with polycystic ovary syndrome (PCOS). Methods: 158 women with PCOS who had treated in hospital affiliated to Xuzhou medical university from June 2015 to December 2017 were in study group, and during the same period, 89 healthy women from who had accepted physical examination were selected into control group. The serum PSA, T and DHEAS levels of all women in both group were compared, and the serum PSA, T and DHEAS levels of women in study group were compared before and after treatment. The correlations among the serum serum PSA, T and DHEAS levels and their diagnostic efficacy were analyzed. Results: The serum PSA, T and DHEAS levels of women in study group were significant higher than those of women in control group (P<0.05). In study group, the serum PSA, T and DHEAS levels of women before treatment were significant lower than those after treatment (P<0.05). Serum PSA, T and DHEAS levels were correlated in study group. The area under PAS curve was 0.689, and the sensitivity and specificity was 0.768 and 0.550, respectively. The area under T curve was 0.812, and the sensitivity and specificity was 0.783 and 0.737, respectively. The DHEAS area under the curve was 0.760, sensitive and specific degree was 0.522 and 0.900, respectively. The joint detection area under the curve was 0.886, which was significant higher than that of individual indicator, and sensitivity and specificity was 0.768 and 0.875, respectively. Conclusion: The levels of serum PSA, T and DHEAS detected can be used as the markers of androgen increasing of women with PCOS, and the combined detected level of serum PSA, T and DHEAS can increase the diagnosis efficiency of PCOS.
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