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| Influence of interventional uterine artery embolization on the fertility function and prognosis of patients with uterine scar pregnancy caused by cesarean section |
| Xianyang Central Hospital of Shaanxi Province, Shaanxi |
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Abstract Objective: To explore the influence of interventional uterine artery embolization (UAE) on the fertility function and prognosis of patients with uterine scar pregnancy (CSP) caused by cesarean section. Methods: 80 patients with CSP in Xianyang central hospital of Shaanxi province from February 2013 to February 2016 were selected as the subjects and were randomly divided into observation group (n=40) and control group (n=40) according to random number table. The patients in observation group were treated by UAE + methotrexate (MTX) + curettage under the monitoring of B ultrasonic, and the patients in control group were treated by MTX+ curettage under the monitoring of B ultrasonic. The clinical effects of patients in the two groups were observed and compared. Results: The intraoperative blooding amount, vaginal bleeding time, and hospitalization time of patients in observation group were significantly less than those of patients in control group (P < 0.05), but there was no significant difference in the level of β-HCG between the two groups after operation (P > 0.05). The total effective rate in observation group after treatment (90.0%) was significant higher than that (65.0%) in control group (P < 0.05). 1 months after treatment, the level of β-HCG of patients in observation group was significant lower than that of patients in control group (P < 0.05), but there was no significant difference in the levels of FSH, LH and E2 between the two groups (P > 0.05). The incidence of adverse reactions of patients in observation group (5.0%) was significant lower than that (20.0%) of patients in control group (P < 0.05). The time of level of β-HCG recovery to normal and recovery time of menstruation of patients in observation group were significant shorter than those of patients in control group (P < 0.05), and the proportion of repeated CSP in observation group were significant lower than that in control group (P < 0.05). There were no significant difference in menstrual cycle and the rate of normal pregnancy between the two groups (P > 0.05). Conclusion: UAE is effective for treating uterine scar pregnancy after cesarean section, which can reduce the clinical symptoms effectively and has good prognosis with less adverse reactions and high safety.
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