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Abstract To explore the clinical effect of epidural combined intravenous anesthesia in laparoscopic hysterectomy. Methods: The data of 80 patients who experienced laparoscopic hysterectomy in Xuancheng people's hospital from January 2014 to December 2016 were collected. According to the different anesthesia methods, patients were divided into the observation group and the control group, 40 cases in the observation group were given epidural anesthesia combined with general anesthesia, and 40 cases in the control group were given intravenous anesthesia. The anesthesia effect, postoperative extubation time, spontaneous breathing recovery time, awake time, rate of postoperative agitation, nausea and vomiting, operation time, total hospitalization expenses and the rate of postoperative additional analgesic drugs of patients in the two groups were compared. Results: Compared to the control group, the total effective rate of patients in the observation group was significantly higher (97.5% vs. 80%), and the difference had statistically significant (P<0.05). Furthermore, the tracheal extubation time, spontaneous breathing time, and awake time of patients in the observation group were significant shorter than those of patients in the control group (P<0.05), and the incidence of postoperative agitation and the additional analgesic drugs rate of postoperative additional analgesic drugs analgesia were significantly lower than those of patients in the control group (P<0.05). However, the operation time, hospitalization expenses and incidence of adverse reactions of patients had no significantly different between the two groups (P>0.05). Conclusion: The effect of epidural combined intravenous general anesthesia used for laparoscopic hysterectomy is better than intravenous anesthesia alone, and it does not increase the rate of adverse effects of surgery and the total cost of hospitalization, so it is worthy of clinical application.
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