|
|
|
Abstract Objective: To evaluate the effect of goal-direct therapy (GDT) on perioperative microcirculation in patients with ectopic pregnancy and hemorrhagic shock. Methods: Sixty adult patients suffering hemorrhagic shock with Ⅱ to Ⅲ of ASA score were randomly divided into two groups: the observation group (goal-direct therapy) and the control group (conventional infusion). Dynamic electrocardiogram (ECG), MAP, central venous pressure (CVP) and cardiac output (CO) were monitored. And heart rate (HR), CVP, MAP and serum lactate level, urinary volume were recorded at different times of 30 min before operation (T1), at 30 min (T2), 1 h (T3) and 1 h (T4) after beginning of the operation and the end of the operation (T5). Results: HR was highest while MAP and CVP were lowest at T1 in two groups (P<0.05). At T2 and T3, HR in the observation group was lower than that of the control group, while MAP and CVP in the observation group were higher than those of the control group (P<0.05). After the treatment, the serum lactate level at T3 and T4 were lower and the urinary volume at T3, T4 and T5 were higher in the observation group when compare with the control group (P<0.05). Conclusion: The stable hemodynamics and balanced microcirculation can be maintained by GDT in patients suffering hemorrhagic shock due to ectopic pregnancy.
|
|
|
|
|
|
|
|
