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Abstract Objective: To explore the clinical effect of carboprost tromethamine to prevent abnormal hemorrhage of scar uterine cesarean delivery and cost. Methods: The study was a prospective controlled clinical trial. 241women experienced scar uterine cesarean delivery were divided randomized into two groups , 126 women was in carboprost tromethamine(CT) injection group and 115 women was in saline injection group. The amount of bleeding during and after operation, rate of postpartum hemorrhage，rate of blood transfusion, total hospitalization expense and human resource cost were compared in the two groups. Results: When compared to saline injection group, amount of bleeding during and after operation, rate of postpartum hemorrhage，and rate of blood transfusion were all much less in injection CT group (P<0.05). Though total hospitalization expense in CT injection group was same as in saline injection group (P>0.05), cost of drug and nursing were less. Furthermore, time of operation ,time of hospitalization and downtime of family members were all shorter (P<0.05).Conclusion: Carboprost tromethamine can reduce the amount of bleeding during and after operation of women with scar uterine cesarean delivery, and it do not increase total hospitalization expense.
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