Abstract Objective: To explore the effects of different promoting cervical mature and induced labor methods for patients with premature rupture of membranes at full-term and near full-term. Methods: From January 2012 to January 2015 in the first people's hospital of Taizhou, a total of 450 pregnant women with premature rupture of membranes were recruited, whose gestational age were all over 35 weeks. According to wills of the women and their families, these included women were divided into observation group (n = 340) and control group (n = 110). The observation group included women with cervical mature (n = 225) and women with cervical immature (n = 115), and all of them had been induced immediately. Women in control group had been induced after waiting for 8-12hours. The outcomes included state of Labor , labor time, rate of amniotic fluid dyeing dung, delivery way, postpartum hemorrhage, and morbidity of mother and baby in perinatal, and analysis the rate over stimulate uterine and other adverse effects after using Dinoprostone. Results: In observation group, there was no statistical significance differences for postpartum hemorrhage, intrauterine infection, puerperal disease and neonatal morbidity of patients with cervical mature compared with that of cervical immature group(χ2 = 0.001, 2.943, 1.951, 2.943, P> 0.05).The incidence of postpartum hemorrhage in the observation group and the control group was no significant difference (χ2= 0.393, P > 0.05). The incidence rates of intrauterine infection, puerperal disease and neonatal morbidity of observation group were significant lower than those of control group (χ2 = 10.621, 17.413 and 14.130, P < 0.05). Rate of amniotic fluid turbidity of cervical immature group was higher than that of cervix mature group (χ2= 39.393, P < 0.05). The time of total labor of observation group was significantly shorter than that of control group (t = 3.0782, P < 0.01). Rate of vaginal delivery of observation group was higher than that of control group (χ2= 6.973, P > 0.05). There was no any serious adverse incident in both groups. Conclusions: Deciding induced labor way according to cervical maturity make obvious advantage for decreasing morbidity of perinatal mother and baby, and can short labor time.
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